In vitro and ex vivo studies
A graduate of the Master’s degree programme in Biology with a specialisation in Molecular Biology at Jagiellonian University. He has extensive experience gained through participation in numerous research projects and collaboration with the pharmaceutical sector. He has experience in managing small teams executing tasks within projects co-funded by the European Union grants. An advocate for the application of new technologies in scientific research. His scientific interests include the use of cellular engineering in discovering biologically active compounds as potential new drugs. He is also passionate about exploring novel therapies for Parkinson’s disease.
The CF4A Module – Ex Vivo and In Vitro Research – is comprised of three laboratories: In Vitro, Biochemical, and Histological. This unit was established to provide a comprehensive set of analytical, biochemical, and histological methods that can be utilised to identify and validate the molecular mechanisms of action of drug candidates. The results obtained using the module’s infrastructure will assist in determining whether a selected compound has a realistic potential to become an effective therapeutic agent and in preparing the data necessary for planning further research.
Key Equipment:
- Seahorse XF Pro (Agilent): A unique instrument for functional analysis of cellular energy metabolism.
- ProteinSimple Jess (Biotechne): Equipment that fully automates the Western blot technique, from electrophoresis to analysis.
- Amersham Typhoon 5 (Cytiva): A multifunctional scanner for biomolecular imaging, including quantitative proteomics analyses using DIGE and large-format digital autoradiography.
- HPLC-EDC: High-Performance Liquid Chromatography System with electrochemical detector.
A detailed description of the above equipment can be found on the Equipment page.
Additional Laboratory Equipment:
- Leica HistoCore Arcadia C and H: A modern, dual-module paraffin embedding station with microprocessor-controlled heating and cooling modules.
- Leica HistoCore Autocut: An automatic rotary microtome.
- Leica VT 1200S Vibratome: An automatic vibrating microtome.
- Leica IP C: A histopathological cassette printer.
- Leica HistoCore Water Bath: Used for flattening paraffin sections in routine paraffin preparation.
- Leica HistoCore Slide Dryer: A slide-drying system.
- Optatech: A slide printer for basic laboratory operations.
A full list of available equipment can be found in the Laboratory of in vitro and ex vivo studies.