Bioanalysis HTS and Pharmacokinetics and Metabolism
Graduate in Biophysics at the Faculty of Biochemistry, Biophysics and Biotechnology of the Jagiellonian University in Krakow. He obtained his PhD in Pharmaceutical Sciences from the Faculty of Pharmacy, Collegium Medicum, Jagiellonian University. He specialises in modern high-throughput in vitro and in silico methods, with emphasis on structure-activity relationship analysis. His research focuses on the search for biologically active substances acting on the central nervous system. He has extensive experience gained from numerous research projects and from working in the pharmaceutical and biotechnology sectors.
The CF3 a,b module consists of two laboratories:
Laboratory of Pharmacokinetics and Metabolism dedicated to rapid and efficient analyses of prototype drugs and active substances, equipped with a high-performance liquid chromatography system for studying the effects of drug candidates on the function of cytochrome P450 isoenzymes involved in drug metabolism and the neuroendocrine regulation of cytochrome P450 system function. In turn, the system for the live study of metabolic pathways can be used in the context of cellular alterations occurring in neuropsychiatric and neurodegenerative diseases and to monitor the ability of prototype compounds to reverse pathological effects.
Laboratory of High-throughput Screening is equipped with equipment to automate and increase the throughput of cellular experiments and biochemical analyses.
For a full list of equipment available in the Laboratory, see Bioanalysis.